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Keep track of Intently (one)pentobarbital will decrease the level or result of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers could lead on to a reduce in fentanyl plasma concentrations, insufficient efficacy or, quite possibly, impro